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HIV-1 Human Interaction Database

HIV-1 Human Interaction Database

 Health Databases / by Animut Mesfin / 103 views

The HIV-1, human interactions project collates published reports of two types of interactions – protein interactions, and human gene knock-downs that affect virus replication and infectivity (‘replication interactions’).  The project aims to provide scientists in the field of HIV/AIDS research a summary of all known interactions of HIV-1 and the human host including human genes that have been reported to affect viral replication and infectivity, interactions between HIV-1 proteins with host cell proteins, other HIV-1 proteins, or proteins from disease organisms associated with HIV/AIDS. The database tracks: NCBI Reference Sequence (RefSeq) protein accession numbers; NCBI Entrez Gene ID numbers; amino acids from each protein that are known to be involved in the interaction; brief description of the protein or replication interaction and keywords to support searching for interactions.

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