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The CPDB is a single standardized resource of the results of 45 years of chronic, long-term carcinogenesis bioassays. The experiments vary widely in design, histopathological examination and nomenclature, and in the published authors’ choices of what information to publish in their papers. Data are included from experiments reported in the general literature and in the Technical Reports of the National Cancer Institute/National Toxicology Program. Information is given in the CPDB on strain, sex, route of compound administration, target organ, histopathology, author’s opinion about carcinogenicity, and reference to the published paper, as well as quantitative data on statistical significance, tumor incidence, dose-response curve shape, length of experiment, duration of dosing, and dose-rate.

 Non-communicable diseases / 99 views

The PDQ health professional cancer information summaries are part of the comprehensive, evidence-based, up-to-date cancer content made available as a public service of the USA National Cancer Institute. They are intended to improve the overall quality of cancer care by informing and educating health professionals about the current published evidence related to individual cancer-related topics and support informed decision making between clinicians and patients.

 Non-communicable diseases / 130 views

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